Endometrial hyperplasia is proliferation of endometrial glands of the inner lining of the uterus i.e. endometrium. It can progress to endometrial carcinoma.It is basically of two types; Simple and Complex Hyperplasia.
When endometrial hyperplasia left untreated it progresses to endometrial cancer (% - rate of progression).
Progesterone can effectively treat endometrial hyperplasia to control bleeding and prevent progression to cancer. They can serve as prevention of recurrence in those with continued risk factors. Hyperplasia without atypia responds well to progesterone. Multiple regimens of progesterone therapy have been found effective in reversing endometrial hyperplasia, including the following:
If hyperplasia with atypia, definitive treatment is hysterectomy due to the high rate of endometrial cancer.
Endometrial cancer starts in the endometrium, the inner lining of the uterus. It is the most frequently occurring female genital cancer in developed countries whereas in developing countries it is third most common. Endometrial adenocarcinoma occurs during the reproductive and menopausal years. The median age of persons with this malignancy is early in the seventh decade of life, although most patients are aged 50-59 years.
Treatment of endometrial cancer is dependent on the stage of the disease and the patient’s surgical fitness. In general, surgery is recommended. Chemotherapeutic medications such as cisplatin can be used in the management of endometrial carcinoma.
"Authored By Dr.Niraj Mahajan"
MD- Gynecologist, Laparoscopic Surgeon, Uro-gynecologist , Infertility specialist & Cosmetic Gynecologist.Read more [+]